報(bào)告題目：DNA酶促氧化在生長(zhǎng)發(fā)育與疾病發(fā)生中的作用

報(bào)告時(shí)間：2023年3月29日（周三）下午14:00

報(bào)告地點(diǎn)：武漢大學(xué)生命科學(xué)學(xué)院二樓報(bào)告廳

報(bào) 告 人：徐國(guó)良 中國(guó)科學(xué)院院士

主講人簡(jiǎn)介：

徐國(guó)良，中國(guó)科學(xué)院分子細(xì)胞科學(xué)卓越創(chuàng)新中心（生物化學(xué)與細(xì)胞生物學(xué)研究所）研究員，復(fù)旦大學(xué)生物醫(yī)學(xué)研究院教授兼執(zhí)行院長(zhǎng)。1985年獲浙江大學(xué)生物學(xué)系學(xué)士學(xué)位、1988年獲中國(guó)科學(xué)院遺傳所碩士學(xué)位，1993年獲德國(guó)馬普分子遺傳學(xué)研究所博士學(xué)位。先后在德國(guó)馬普分子遺傳學(xué)研究所、美國(guó)哥倫比亞大學(xué)遺傳發(fā)育系和醫(yī)學(xué)系做博士后研究。2001至2006任中國(guó)科學(xué)院與德國(guó)馬普學(xué)會(huì)國(guó)際合作青年科學(xué)家小組組長(zhǎng)，并獲得“國(guó)家杰出青年科學(xué)基金”，2015年當(dāng)選中國(guó)科學(xué)院院士。

徐國(guó)良院士長(zhǎng)期致力于DNA的表觀(guān)遺傳修飾研究，在“DNA甲基化與去甲基化的分子機(jī)制”以及“重編程過(guò)程中的表觀(guān)遺傳調(diào)控機(jī)制”研究領(lǐng)域取得一系列國(guó)際前沿和領(lǐng)先成果，兩次入選“中國(guó)科學(xué)十大進(jìn)展”（2011年、2016年）。2012年獲得第五屆談家楨生命科學(xué)創(chuàng)新獎(jiǎng)，2014年獲得陳嘉庚生命科學(xué)獎(jiǎng)，2017年獲得何梁何利科學(xué)與技術(shù)進(jìn)步獎(jiǎng)。近年來(lái)主要探究表觀(guān)修飾及修飾酶在生長(zhǎng)發(fā)育與腫瘤發(fā)生發(fā)展過(guò)程中的作用機(jī)制。

Brief Introduction of Professor Guoliang Xu

Guoliang Xu, research professor at the Center for Excellence in Molecular Cell Science, CAS, (Shanghai Institute of Biochemistry and Cell Biology), and professor and executive dean at the Biomedical Research Institute of Fudan University. He received his bachelor's degree from the Department of Biology at Zhejiang University in 1985, his master's degree from the Institute of Genetics, Chinese Academy of Sciences in 1988, and his PhD from the Max Planck Institute for Molecular Genetics in Germany in 1993. He did his postdoctoral research at the Max Planck Institute for Molecular Genetics in Germany, the Department of Genetics and Development at Columbia University in the United States, and the Department of Medicine at Columbia University. He served as the leader of the International Young Scientist Group of the Chinese Academy of Sciences and the Max Planck Society from 2001 to 2006, and was awarded the "The National Science Fund for Distinguished Young Scholars". He was elected as a member of the Chinese Academy of Sciences in 2015.

Academician Guoliang Xu has long been committed to the study of epigenetic modification of DNA. He has made a series of internationally leading achievements in the fields of "molecular mechanisms of DNA methylation and demethylation" and "epigenetic regulation mechanisms in reprogramming processes". His works have been twice selected as the "Top Ten Advances in Chinese Science" (2011 and 2016). He won the fifth C.C.Tan Life Science Innovation Award in 2012, the Tan Kah Kee Award of Life Sciences in 2014, and the Ho Leung Ho Lee Science and Technology Progress Award in 2017. His main interest recent years lies in the mechanism of epigenetic modification and modification enzymes in the process of growth and tumor development.