時(shí) 間：2018年5月21日（周一）10:00

地 點(diǎn)：武漢大學(xué)櫻頂老圖書(shū)館

主講人：David W. Christianson 美國(guó)賓夕法尼亞大學(xué)教授

題 目：Structural Biology and Chemistry of Histone Deacetylases in Human Disease and Drug Discovery

主講人簡(jiǎn)介：

David W. Christianson教授于哈佛大學(xué)先后獲得了學(xué)士、碩士以及博士學(xué)位，并在隨后的28年時(shí)間內(nèi)在賓夕法尼亞大學(xué)化學(xué)系開(kāi)展學(xué)術(shù)研究。David W. Christianson教授長(zhǎng)期致力于金屬依賴(lài)性脫乙酰酶，精氨酸酶和萜類(lèi)生物合成酶等酶的結(jié)構(gòu)與功能的研究。迄今為止，已成功在Science，Nature，Nature Structural & Molecular Biology，JACS，PNAS，Nature Communication等多個(gè)國(guó)際頂級(jí)期刊上發(fā)表一系列重要的科學(xué)論文。

他的成就使其獲得了眾多獎(jiǎng)項(xiàng)，包括美國(guó)化學(xué)學(xué)會(huì)頒發(fā)的輝瑞酶學(xué)化學(xué)獎(jiǎng)和生物學(xué)過(guò)程化學(xué)Repligen獎(jiǎng)，哈佛大學(xué)拉德克利夫高級(jí)研究學(xué)院的Elizabeth S.和Richard M. Cashin研究員以及哈佛大學(xué)化學(xué)與化學(xué)生物學(xué)客座教授。

Brief Introduction of Professor David W. Christianson

Professor David W. Christianson received the AB, AM, and PhD from Harvard University before moving to the University of Pennsylvania, where he has been a member of the faculty for 28 years. His current research focuses on structural and function of metal-dependent arginases, deacetylases, and enzymes of terpenoid biosynthesis. At present, he had published series of papers in top professional journals suchas Science,Nature, Nature Structural & Molecular Biology, JACS, PNAS, Nature Communication.

His accomplishments have been recognized by numerous awards, including the Pfizer Award in Enzyme Chemistry and the Repligen Award in Chemistry of Biological Processes from the American Chemical Society, and Fellowships from the John Simon Guggenheim Memorial Foundation, the Radcliffe Institute for Advanced Study at Harvard University, and the visiting Professor of Chemistry and Chemical Biology of Harvard University.